MyNewsLA.com photo by John Schreiber.

One person was severely injured and is in the hospital Friday after a SUV collided head on with a big rig in Palmdale.

Officers from the California Highway Patrol were called at 11:49 p.m. Thursday to Avenue M near 50th Street East where the driver of a Yukon Denali collided with the semi trailer, CHP Officer Patrick Kimball told City News Service.

The crash left fluids spilled on the roadway and a Los Angeles County Hazmat unit was called to assist with the cleanup.

The driver of the SUV was taken to Antelope Valley Hospital with serious injuries and the driver of the big rig was uninjured.

Kimball said the cause of the crash is under investigation.

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