Police Saturday asked for public assistance to find a 46-year-old man with Down syndrome who went missing in Los Angeles.

Andre Henri Jackson was last seen about 2:30 p.m. on Christmas Day in the 1400 block of Grand Avenue, near California Hospital, according to the Los Angeles Police Department’s 77th Street Division watch commander.

Jackson many have boarded MTA Bus 33 headed west to Venice Boulevard, the LAPD said.

He is Black with gray/black hair, brown eyes and a large build. He stands 4 feet, 11 inches tall and weighs about 180 pounds, the LAPD reported.

He was last seen wearing a black-hooded sweater, black jogging pants with a Sketchers emblem and blue Sketchers shoes, police said.

Anyone with information on his whereabouts was asked to call the LAPD’s 77th Division at 323-786-5409 or the 24/7 tipline at 877-527-3247 or 911. Tipsters can also call Crime Stoppers at 800-222-8477.

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