UCLA engineers and scientists have demonstrated that treatments with near-room-temperature, cold atmospheric plasma can kill the coronavirus present on a variety of common surfaces in as little as 30 seconds, the university announced Monday.

The study marks the first time cold plasma has been shown to effectively and quickly disinfect surfaces contaminated with the SARS-CoV-2 virus that causes COVID-19, according to UCLA.

The novel coronavirus can remain infectious for tens of hours on surfaces, so the advance is a major breakthrough that may help slow the spread of the virus, according to the study published in the journal Physics of Fluids.

“This is a really exciting result, showing the potential of cold atmospheric plasma as a safe and effective way to fight transmission of the virus by killing it on a wide range of surfaces,” said study leader Richard Wirz, professor of mechanical and aerospace engineering at the UCLA Samueli School of Engineering.

Plasma, not to be confused with blood plasma, is an electrically charged gas known as the fourth state of matter — solid, liquid and gas being the others — with electrons and charged ions accounting for its main makeup.

The researchers created the plasma by subjecting air and argon gas — a common, non-toxic gas — to a strong electric field across electrodes inside a spray jet built by a 3D printer. The resulting ionized, atmospheric cold plasma remains stable at room temperatures.

The team used the jet to spray plastic, metal, cardboard and leather surfaces laced with SARS-CoV-2 cultures. The jet ionized the surrounding air, turning it into cold atmospheric plasma and killing most of the virus after 30 seconds. The team saw similar results with cotton from face masks.

Leather from a basketball, football and baseball was included to test effectiveness in disinfecting sports equipment and to simulate the rough and wrinkled surface of skin.

Cold plasma has previously been shown in research studies to be effective in cancer treatment, wound healing, dental-instrument disinfection and other applications.

An important advantage of plasma is that it can be safely used on a variety of surfaces without damaging them, while treatments with chemicals and UV light cannot be used effectively on porous surfaces like cardboard and skin without damage.

Another advantage is an estimated lower cost for supplies compared to standard chemical sanitizers. The researchers are working with campus units at UCLA to further test the system.

“This eco-friendly, innovative technology could be implemented to prevent the transmission of SARS-CoV-2 in hospitals, transportation and sports settings,” said study co-author Vaithi Arumugaswami, an associate professor of molecular and medical pharmacology at the David Geffen School of Medicine at UCLA.

According to Wirz, cold plasma may even be a potential candidate, pending further study, to kill the coronavirus when it is airborne.

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