A wind-driven brush fire that exploded across more than 4,700 acres overnight continued to rage in the northern San Fernando Valley Friday, forcing the evacuation of roughly 100,000 people and closure of multiple freeways and schools, while causing at least one death.

The blaze was reported just after 9 p.m. Thursday off the westbound Foothill (210) Freeway near Yarnell Street and Saddle Ridge Road in Sylmar and quickly spread due to wind-blown embers that jumped the Golden State (5) Freeway about 11:20 p.m., spreading the flames into Granada Hills and Porter Ranch, according to Margaret Stewart of the Los Angeles Fire Department.

As of 7:30 a.m., the fire had burned more than 4,700 acres with no containment, Los Angeles Fire Department Chief Ralph Terrazas said. Authorities said the blaze was moving at a pace of about 800 acres an hour, meaning the inferno was likely to explode in size amid red flag fire conditions that included gusting Santa Ana winds and single-digit humidity.

Terrazas said at least 25 homes had been damaged, if not destroyed. One person, described only as a man in his 50s, died of a heart attack Friday morning. Terrazas said the man was talking to firefighters when he went into cardiac arrest. Media reports indicated the man was trying to protect his home in Porter Ranch from the flames. Fire officials said the man was taken to a hospital, where he was pronounced dead.

The massive fire prompted a mandatory evacuation order for all residents of Porter Ranch north of the Ronald Reagan (118) Freeway from Reseda Boulevard to DeSoto Avenue, Stewart said. Residents of Granada Hills from Balboa Boulevard and north of Sesnon Boulevard to the Ventura County border were under a mandatory evacuation order. An evacuation warning was issued for all areas south of Sesnon Boulevard to the Ronald Reagan (118) Freeway, Stewart said.

An evacuation warning is issued when a mandatory evacuation is anticipated. Residents in this area should be prepared to evacuate immediately, Stewart said.

Mandatory evacuations were also issued for the Oakridge Estates community north of the Foothill Freeway in Sylmar.

The evacuation orders affected roughly 23,000 homes — equating to about 100,000 people, authorities said.

Evacuation centers were established at the Sylmar Recreation Center, 13109 Borden Ave.; the Mason Recreation Center, 10500 Mason Ave. in Chatsworth; and the Granada Hills Recreation Center, 16730 Chatsworth St. As of Friday morning, the Mason and Granada Hills shelters had already reached capacity, and the Sylmar center was nearing capacity.

That prompted authorities to open a fourth evacuation center at Northridge Recreation Center, 18300 Lemarsh St.

Large animals can be taken to the Hansen Dam Recreation Area at 11770 Foothill Blvd. in Lake View Terrace or the West Valley Animal Shelter at 20655 Plummer St. in Chatsworth, Stewart said.

The Granada Hills Recreation Center at 16730 Chatsworth St. was full as of about 4:20 a.m. and no longer able to accept evacuees, Stewart said.

About 330 juveniles and staff from the Barry J. Nidorf Juvenile Hall at 16350 Filbert St. were evacuated Friday morning, ABC7 reported.

Authorities urged residents to heed evacuation warnings for their own safety.

“When you’re told to leave, we mean for you to leave,” Los Angeles Police Department Chief Michel Moore said Friday morning. “It’s for your safety, it will save your life. If you stay in those areas we cannot guarantee you that we’ll be able to find you if you’re overcome by flames.”

Roughly 1,000 firefighters from LAFD, Los Angeles County Fire Department and Angeles National Forest were on the ground battling the flames and eight water-dropping helicopters were deployed. Fixed-wing air tankers were also being sent to the fire.

The Los Angeles Department of Water & Power reported overnight that about 2,500 customers had lost power in the Granada Hills and Sylmar areas. The utility noted that much of the power to Porter Ranch is provided through underground lines, but there had been damage to two overhead circuits and 16 power poles. As of about 8 a.m., DWP reported that 870 customers were without power.

The utility had cut power to some overhead power lines Thursday night to assist with the firefighting efforts. The placement of the power lines in the area added to the hazards facing helicopter pilots trying to drop water on the flames.

The LAPD issued a citywide tactical alert Thursday night in response to the fire. It allows the department to keep officers beyond the end of their shifts.

“(We) are working with LAFD to carry out any necessary evacuations,” the LAPD tweeted. “If you live in the area of the 210 freeway and Yarnell (Street) in Sylmar, we urge you to be prepared & follow all public safety instructions.”

Moore said that because of the tactical alert “we’re stretched thin.”

LAPD Mission Division officers were clearing traffic in Sylmar due to the fire.

“Please steer clear away from the area of westbound Foothill (Boulevard) to Roxford (Street),” the Mission Division tweeted. “Avoid the 210 freeway as well. Thank you.”

The flames also created a traffic nightmare, with all freeways from the north into the Porter Ranch area blocked. According to the California Highway Patrol, closures were implemented on:

— the Golden State (5) Freeway southbound from Calgrove Boulevard and northbound from Roxford Street;

— southbound Antelope Valley (14) Freeway at Newhall Avenue;

— Sierra Highway at Newhall Avenue;

— The Old Road at Calgrove Boulevard;

— the Foothill (210) Freeway from the 5 Freeway to the Ronald Reagan (118) Freeway;

— westbound 118 Freeway at Balboa Boulevard;

— eastbound 118 Freeway from the Ventura County line to Tampa Avenue; and

— the northbound San Diego (405) Freeway at the 118 Freeway.

The Los Angeles Unified School District canceled classes at virtually all campuses in the area, and all schools in the Castaic Unified and Newhall school districts were shuttered. Cal State Northridge was closed, along with Los Angeles Pierce College, Los Angeles Mission College and Los Angeles Valley College.

There was no immediate word on what sparked the blaze. Terrazas noted that city officials had been working with the Los Angeles Homeless Services Authority to clear homeless people out of fire-prone areas during the red-flag conditions that began Thursday, but he said he did not know if there were any encampments near the flashpoint of the blaze.

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