Police Sunday circulated a photo of a 46-year-old man with Down syndrome who went missing Friday in downtown Los Angeles.

Andre Henri Jackson was last seen Friday at about 2:30 p.m. in the 1400 block of Grand Avenue near Dignity Health-California Hospital Medical Center, the Los Angeles Police Department reported.

Jackson may have boarded MTA bus line 33 westbound on Venice Boulevard, police said.

He was described as a 4-feet-11-inch tall Black man with a large build weighing 180 pounds with black hair and brown eyes. He was last seen wearing a black hooded sweater, black jogging pants with a “Skechers” emblem and blue Skechers tennis shoes.

The LAPD’s 77th Street station urged anyone with information regarding Jackson’s whereabouts to call them at 323-786-5075 or LA Regional Crime Stoppers at 800-222-8477.

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