Two women and two young boys were killed Friday in a wrong-way crash involving a big rig and a car in Lancaster, and a third child was hospitalized with serious injuries.

The collision, which left a black Dodge Challenger crumpled and the big rig’s cab overturned, occurred at 9:11 a.m. at the intersection of East Avenue G and North 30th Street East, according to the Los Angeles County Fire Department.

The Dodge was traveling in the wrong direction in the eastbound lane of Avenue G and collided head-on with the truck, according to the California Highway Patrol.

The driver of the Dodge died at the scene, and the CHP initially reported that her four passengers — three children and a woman — were taken to hospitals in critical condition.

CHP officials subsequently told reporters that doctors were unable to save the woman and two boys, one aged 10 or 11, and the other about 7 to 9, according to the CHP. A third child, around 5 years old, was being treated for “major traumatic injuries,” the CHP reported.

CHP said the trucker sustained minor injuries and was not transported for hospital treatment.

The victims’ names were withheld pending family notification.

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