Homer Simpson is tempted by his pharmacist, voiced by “Girls” star Lena Dunham, in the cartoon’s 27th season as his marriage goes on the rocks.

Al Jean, executive producer of “The Simpsons,” told Variety: “It’s discovered after all the years Homer has narcolepsy — a chronic neurological disorder that affects the control of sleep, causing uncontrollable episodes of falling asleep, even during activities that demand attention — and it’s an incredible strain on the marriage.

“Homer and Marge legally separate, and Homer falls in love with his pharmacist, who’s voiced by Lena Dunham.”

Homer’s vote in the presidential election also is in play.

“We’re definitely going to have Homer vote in 2016,” Jean said. “He voted for Romney in 2012 because he invented Obamacare. He tried to voted for Obama in 2008 but all his votes went to McCain.”

Homer’s choice will be a kiss of death, however.

“We’re not sure who the candidates are yet, but whatever he wants it’s not going to happen,” Jean said.

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