A new round of overnight lane and ramp closures will begin Tuesday on the San Diego (405) Freeway through the Sepulveda Pass, following the Labor Day holiday, as crews continue work on a $143.7 million pavement rehabilitation project.

The closures are scheduled from 9 p.m. to 6 a.m. Tuesday through Friday for K-rail installation and paving work, according to Caltrans.

Up to four northbound lanes will be closed between Wilshire Boulevard and Skirball Center Drive/Mulholland Drive, while up to three northbound lanes will be closed between Sepulveda and Victory boulevards.

Northbound 405 ramps at Wilshire Boulevard, Sunset Boulevard, Moraga Drive and Getty Center Drive will also be affected by closures.

On the southbound side, up to four lanes will be closed between the Ventura (101) Freeway and Skirball Center Drive/Mulholland Drive. The Sepulveda Boulevard and Ventura Boulevard on-ramps to the southbound 405 and the southbound off-ramp to Ventura Boulevard will also be closed.

The speed limit will be reduced to 55 mph in certain sections of the northbound and southbound 405 because of the ongoing paving work, according to Caltrans.

The work is part of the I-405 Pavement Rehabilitation Project between Van Nuys and Westwood, which is intended to improve safety and mobility and extend the life of the freeway pavement.

Residents and businesses near the construction may experience noise, vibrations and dust, Caltrans said.

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