A 22-year-old man died Saturday and at least one other person was injured in a multiple-vehicle crash on the Santa Ana (5) Freeway in Santa Ana.

Luis Manuel Salina Garcia was a Santa Ana resident, according to the Orange County coroner’s office.

The crash occurred at 3:20 a.m. in the southbound Santa Ana Freeway at 17th Street, the California Highway Patrol reported.

It involved a Honda Pilot and possibly a Mitsubishi, the CHP said.

Salina Garcia was pronounced dead at the scene and paramedics rushed at least one person to Orange County Global Medical Center, the CHP said..

All traffic lanes at the site of the crash were reopened at 5:58 a.m.

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