A two-vehicle crash involving a big rig on the southbound Santa Ana (5) Freeway in the La Mirada area Monday prompted closure of lanes in both directions as a precaution while crews worked to clear the scene, causing a major traffic tie-up affecting scores of motorists.

The non-injury crash was reported at about 10:15 a.m. south of Valley View Avenue, according to the Los Angeles County Fire Department.

Some fuel spilled onto the southbound lanes and then spread onto the northbound lanes, and a hazardous materials team was sent to the scene, the fire department reported.

Several southbound lanes were blocked — along with all northbound lanes — as crews worked to remove debris and about 300 gallons of spilled diesel fuel and non-toxic glycolic acid, a substance used in beauty supply products.

At about 1:30 p.m., all southbound lanes also were closed for the cleanup effort, according to Caltrans.

All lanes were cleared and reopened at about 6:30 p.m., according to the California Highway Patrol

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