Two motorists were killed in Highgrove Tuesday after one of them drove the wrong way into traffic on Interstate 215, causing a head-on collision, according to the California Highway Patrol.

The fatal wreck happened about 12:30 a.m. on the northbound side of the 215, near Center Street.

CHP Officer Juan Quintero said that the driver of a Ford Fusion, whose identity was not immediately released, entered the northbound side of the freeway going south around the Interstate 10/215 interchange in San Bernardino.

There were several 911 calls alerting law enforcement to the deadly hazard, and Quintero said CHP officers responded.

Before they could find the wrongway driver, however, the suspect entered the carpool lane and slammed head-on into a Ford Focus, according to the CHP spokesman.

Riverside County Fire Department crews reached the location within a few minutes and extricated the two motorists, both of whom were pronounced dead at the scene.

The victim in the Focus also was not identified. Neither vehicle was carrying passengers.

The freeway was partially shut down for over three hours while the wreckage was cleared a preliminary investigation was conducted.

Quintero said that it is unknown whether drugs or alcohol may have been factors in the crash.

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